摘要
临床流行病学数据显示,糖尿病对新型冠状病毒肺炎(COVID-19)的发生和病情进展有负面影响,但其机制尚不确定。中东呼吸综合征(MERS)是另外一种冠状病毒感染性疾病,最近有文献就其与糖尿病的关系进行了深入的基础研究。本文对该文献和其他相关研究作一介绍,并在此基础上就如何借鉴MERS的研究思路和方法,为开展糖尿病影响COVID-19的机制研究提出一些思考性问题。
Epidemiology studies suggest that comorbid diabetes may have some negative impacts on the development and progression of the coronavirus disease 2019(COVID-19).However,the exact mechanisms remain to be unclear so far.A recent study on another type of coronavirus infection,Middle East respiratory syndrome(MERS),was investigated along with its relationship with diabetes.This essay aims to give a brief introduction to this report and related studies,and to propose some suggestions on what we may learn from these investigations to conduct further studies on the potential mechanisms underlying the effects of diabetes mellitus on COVID-19.
作者
杨思珏
关海霞
Yang Sijue;Guan Haixia(Liaoning Provincial Key Laboratory of Endocrine Diseases,Institute of Endocrinology,Department of Endocrinology and Metabolism,the First Hospital of China Medical University,Shenyang 110001,China)
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2020年第3期191-194,共4页
Chinese Journal of Endocrinology and Metabolism
关键词
冠状病毒
新型冠状病毒肺炎
中东呼吸综合征
糖尿病
机制
Coronavirus
Coronavirus disease 2019
Middle East respiratory syndrome
Diabetes mellitus
Mechanism
