青年癫痫患者幽默特点及与抑郁的相关性

The humor characteristics of young epileptic patients and its correlation with depression

目的探讨青年癫痫患者幽默感特点及其与抑郁之间的相关性。方法采用多维幽默感量表(MSHS)、幽默风格问卷(HSQ)以及贝克抑郁量表(BDI-Ⅱ)对2018年10月至2019年3月就诊于皖南医学院神经内科门诊的55例青年癫痫患者和44名健康对照进行评估。结果青年癫痫患者组幽默创造得分、幽默应对得分以及幽默总分[分别为(25.3±5.9)分、(16.7±5.0)分、(61±10)分]明显低于正常对照组[分别为(29.8±6.1)分、(21.1±2.6)分、(71±8)分];青年癫痫患者幽默风格问卷中自强型幽默得分明显低于正常对照组[(18±7)分比(23±6)分],而自贬型幽默得分明显高于对照组[(14±5)分比(9±3)分];BDI-Ⅱ评分青年癫痫患者得分明显高于健康对照[(13±7)分比(6±4)分]。相关分析显示:抑郁得分与幽默创造、幽默应对、MSHS总分以及自强型幽默得分呈负相关(r=-0.566^-0.721,P<0.05),而与自贬型得分呈正相关(r=0.818,P<0.05)。临床相关因素中,抑郁得分与控制与否及性别相关。回归分析显示:幽默应对、自贬型幽默得分与自强型幽默得分是癫痫患者抑郁的预测因素。结论青年癫痫患者存在幽默感的缺失以及幽默风格的改变,这种幽默感的缺失以及幽默风格的改变与患者出现抑郁存在关联。

Objective To explore the characteristics of humor in young adult epileptic patients and examine the relationship between humor and depression.Methods We recruited 55 young adult epileptic patients who visited outpatient clinic of the Department of Neurology of Yijishan Hospital of Wannan Medical College between October 2018 and March 2019 and 44 healthy controls to complete the multidimensional humor scale (MSHS), humor style questionnaire (HSQ) and Beck depression scale-Ⅱ (BDI-Ⅱ), and compared their differences between the two groups.Results The results showed that the young adult patients with epilepsy (PWEs) were affected in humor creation, coping with humor and the totally scores of MSHS. The scores of humor creation, coping with humor and the totally scores of MSHS in the young epilepsy patients were 25.3±5.9, 16.7±5.0 and 61±10, which were significantly lower than those in the control group 29.8±6.1, 21.1±2.6 and 71±8. As for the humor style, self-defeating humor scores in PWEs were higher than controls 14±5 vs 9±3, and the self-enhancing humor scores were lower than controls 18±7 vs 23±6. The scores of BDI-Ⅱ in PWEs were significantly higher than those of normal controls 13±7 vs 6±4. Pearson′s correlation test showed that the scores of BDI-Ⅱ were negatively correlated with humor creation, coping with humor, the totally scores of MSHS and self-enhancing humor scores (r=-0.566—-0.721, P<0.05), while it was positively correlated with self-defeating humor scores (r=0.818, P<0.05). Among the clinically relevant factors, the scores of BDI-Ⅱ were correlated with seizure control and gender. Multiple stepwise linear regression showed that coping with humor, self-defeating and self-enhancing humor scores were closely related with depression in young epileptic adults.Conclusion The young adults with epilepsy are affected in sense of humor and humor style, which are closely related with depression.