中药结肠透析对慢性重型肝炎患者肝功能及预后的影响

Effect of Traditional Chinese Medicine Colon Dialysis on Liver Function and Prognosis of Chronic Severe Hepatitis

目的探讨中药结肠透析对慢性重型肝炎患者肝功能及预后的影响。方法选择2015年4月-2018年6月收治的慢性重型肝炎患者共80例,随机分为观察组(40例)和对照组(40例)。对照组给予综合治疗,观察组给予中药结肠透析治疗,对比2组肝功能及并发症发生情况,并记录2组生存率。结果观察组患者谷丙转氨酶(ATL)、总胆红素(TBil)水平均低于对照组患者,而胆碱酯酶(CHE)、血浆白蛋白(ALB)水平均高于对照组,差异有统计学意义(P<0.05);观察组患者并发症发生率低于对照组患者,差异有统计学意义(P<0.05);观察组患者生存率高于对照组患者,差异有统计学意义(P<0.05)。结论中药结肠透析治疗慢性重型肝炎患者疗效显著,可有效改善患者肝功能,并明显降低其并发症发生率,提高患者生存率,值得在临床应用。

Objective To investigate the effect of traditional Chinese medicine colon dialysis on liver function and prognosis in patients with chronic severe hepatitis. Methods From April 2015 to June 2018, 80 patients with chronic severe hepatitis were randomly divided into observation group(n=40) and control group(n=40). The control group was given comprehensive treatment, and the observation group was treated with traditional Chinese medicine colon dialysis. The liver function and complications of the two groups were compared, and the survival rates of the two groups were recorded. Results The total bilirubin(TBil) and glutamic pyruvic transaminase(ATL) level in the observation group was lower than that in the control group, while cholinesterase(CHE) and the plasma albumin(ALB) level in the observation group was significantly lower than that of the control group, and the difference was statistically significant(P<0.05). The incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05). The survival rate of the patients in the observation group was significantly higher than that in the control group, and the difference was statistically significant(P<0.05). Conclusion Traditional Chinese medicine colon dialysis is effective in the treatment of chronic severe hepatitis, which can effectively improve the liver function, reduce the incidence of complications and improve the survival rate of patients, which is worthy of clinical application.