全身麻醉与椎管内麻醉用于高龄股骨骨折患者手术中对认知功能及并发症的影响

Effects of general anesthesia and intrathecal anesthesia on cognitive function and complications in elderly patients with femoral fracture

目的探讨全身麻醉与椎管内麻醉用于高龄股骨骨折患者手术中对认知功能及并发症的影响。方法选取2015年8月至2018年8月本院300例高龄股骨骨折手术患者,采用随机数字表法将其分为研究组(n=150,椎管内麻醉)与对照组(n=150,全身麻醉)。比较两组术后认知功能及并发症发生情况。结果术后2、4、8、12、24 h时,研究组MMSE评分均高于对照组(P=0.000);研究组术后并发症总发生率(3.33%)低于对照组(10.00%)(P=0.020)。结论高龄股骨骨折患者术中应用椎管内麻醉对认知功能的影响较全身麻醉小,且并发症更少,值得临床推广。

Objective To investigate the effects of general anesthesia and intrathecal anesthesia on cognitive function and complications in elderly patients with femoral fracture.Methods From August 2015 to August 2018,300 elderly patients undergoing femoral fracture surgery in our hospital were selected and divided into study group(n=150,intrathecal anesthesia)and control group(n=150,general anesthesia)according to the random number table method.The postoperative cognitive function and complications were compared between the two groups.Results At 2,4,8,12 and 24 h after surgery,the MMSE scores in the study group were higher than those in the control group(P=0.000);the total incidence of postoperative complications in the study group(3.33%)was lower than that in the control group(10.00%)(P=0.020).Conclusion The effect of intrathecal anesthesia on cognitive function in elderly patients with femoral fracture is less than that of general anesthesia,and the complications are less,which is worthy of clinical promotion.