核医学显像与多普勒超声诊断在亚急性甲状腺炎中的临床应用

Clinical application of nuclear medicine imaging and Doppler ultrasound diagnosis in subacute thyroiditis

目的探讨核医学显像与多普勒超声诊断在亚急性甲状腺炎中的临床应用。方法选取2011年10月~2013年12月在我院进行诊治的133例亚急性甲状腺炎患者与133例非亚急性甲状腺炎患者作为研究对象,均行核医学显像诊断检查和多普勒超声诊断检查。以细针穿刺细胞学检查结果作为参照,分析核医学显像诊断检查、多普勒超声诊断检查及联合诊断检查的临床诊断价值(灵敏度、特异度、准确度、阳性预测值)。结果核医学显像诊断检查的灵敏度(80.5%)、特异度(83.5%)、准确度(82.0%)均高于多普勒超声诊断检查(69.2%、71.4%、70.3%),联合诊断检查的灵敏度(98.5%)、特异度(97.7%)、准确度(98.1%)均高于核医学显像诊断检查和多普勒超声诊断检查,差异均有统计学意义(P<0.05)。多普勒超声诊断检查、核医学显像诊断检查及联合诊断检查的阳性预测值比较,差异均无统计学意义(P>0.05)。结论核医学显像诊断检查与多普勒超声诊断检查均是亚急性甲状腺炎的有效诊断方法,联合诊断可提高疾病的诊断率。

Objective To investigate clinical application of nuclear medicine imaging and Doppler ultrasound diagnosis in subacute thyroiditis.Methods A total of 133 patients with subacute thyroiditis and 133 patients without subacute thyroiditis treated in hospital from October 2011 to December 2013 were selected,who performed nuclear medicine imaging diagnosis and Doppler ultrasound diagnosis.The results of fine needle aspiration cytology were used as reference.The clinical diagnostic value(sensitivity,specificity,accuracy,positive predictive value)of nuclear medicine imaging diagnostic examination,Doppler ultrasound diagnostic examination and combined diagnostic examination were analyzed.Results The sensitivity(80.5%),specificity(83.5%)and accuracy(82.0%)of nuclear medical imaging diagnostic examination were higher than those of Doppler ultrasound diagnostic examination(69.2%,71.4% and 70.3%),the sensitivity(98.5%),specificity(97.7%)and accuracy(98.1%)of the combined diagnostic examination were all higher than those of nuclear medical imaging diagnostic examination and Doppler ultrasound diagnostic examination,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the positive predictive value of Doppler ultrasound diagnostic examination,nuclear medicine imaging diagnostic examination and combined diagnostic examination(P>0.05).Conclusion Nuclear medicine imaging diagnosis and Doppler ultrasound diagnosis are effective methods in diagnosis of subacute thyroiditis.Combined diagnosis can improve diagnostic rate of diseases.