神经外科介入治疗病人院内感染情况调查及危险因素分析

Investigation of nosocomial infection and analysis of factors relate to it in neurosurgical patients after interventional therapy

目的了解我院神经外科介入治疗病人的院内感染现况,分析感染相关的危险因素,为控制神经介入治疗后院内感染与制定预防措施提供参考。方法回顾性分析2016年1~12月我院神经外科介入治疗的1274例病人的临床资料,统计院内感染率,并对引发院内感染的相关因素进行统计学分析。结果神经外科介入治疗后院内感染率为2.47%,感染类型主要为呼吸系统感染(72.5%),其次为血液系统感染(15.0%)、泌尿系统感染(7.5%)、中枢神经系统感染(5.0%)。多因素logistic回归分析显示低白蛋白血症、低钾血症、术后输血、留置静脉置管是神经外科介入治疗后院内感染的独立危险因素(P<0.05)。结论多种因素与神经外科介入治疗院内感染密切相关,应进行针对性地预防,从而达到减少院内感染的目的。

Objective To provide the basis for controlling the nosocomial infection in the patients after neurosurgical interventional therapy.Methods The clinical data of 1274 neurosurgical patients,who underwent interventional therapy from January,to December,2016,were analyzed retrospectively.The factors related to the nosocomial infection were statistically analyzed.Results Of these 1274 patients undergoing neurosurgical interventional therapy,34(2.67%)suffered the nosocomial infection and 1240(97.33%)not.The infection included respiratory system infection(72.5%),blood system infection(15.0%),urinary system infection(7.5%)and central nervous system infection(5.0%).The nosocominal infection involved two systems in 6 patients.The multivariate logistic regression analysis showed that hypoalbuminemia,hypokalemia,postoperative blood transfusion and indwelling venous catheterization were independent risk factors of the nosocomial infection after neurosurgical interventional therapy.Conclusion It is necessary to carry out the measures directed at the factors which are closely related to nosocomial infection in order to reduce nosocomial infection in the patients receiving neurosurgical interventional therapy.