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微小RNA介导恶性肿瘤多药耐药的研究进展 被引量:2

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摘要 肿瘤的多药耐药性是导致肿瘤化疗失败的重要原因,然而多药耐药的分子机制现在还不能完全阐明。一些特定的miRNA在恶性肿瘤多药耐药的细胞中异常表达,通过广泛参与细胞的各个信号通路的调控,从而介导肿瘤多药耐药的发生,这在临床上具有重要的研究价值,结合国内外miRNA研究内容,旨在对miRNA参与多药耐药的分子机制和临床应用价值等进行综述。
出处 《齐齐哈尔医学院学报》 2020年第1期88-90,共3页 Journal of Qiqihar Medical University
基金 安徽省高校自然科学研究项目(KJ2018A0933)。
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