早产儿纠正胎龄年龄1岁时体格和神经心理发育及其发育商的影响因素

Physical/neuropsychological development and factors influencing development quotient in preterm infants at corrected age of one year

目的探讨早产儿纠正胎龄1岁时与足月儿1岁时体格发育和神经发育差异,分析早产儿纠正胎龄1岁时发育商的影响因素。方法纳入107例早产儿以及103例健康足月儿。比较早产儿纠正胎龄1岁时与足月儿1岁时体格发育及神经心理发育情况,并分析早产儿到正胎龄1岁时发育商的影响因素。结果早产儿纠正胎龄1岁时身高、体重、头围和神经心理发育水平均落后于足月儿1岁时水平(均P<0.05)。出生时体重、喂养方式为早产儿发育商异常的影响因素(均P<0.05)。结论早产儿纠正胎龄1岁时的体格发育、神经心理发育均落后于足月儿。多种因素可影响早产儿神经心理发育,应加强对早产儿的随访监测,并给予科学的干预指导。

Objective To investigate the difference in physical and neuropsychological development between preterm infants at corrected age of one year and full-term infants aged one year,and to analyze the influencing factors of development quotient in preterm infants at corrected age of one year.Methods A total of 107 preterm infants and 103 healthy full-term infants were recruited.The physical and neuropsychological development was compared between preterm infants at corrected age of one year and full-term infants aged one year,and the influencing factors of development quotient in preterm infants at corrected age of one year were analyzed.Results The preterm infants at corrected age of one year exhibited shorter height,less weight,smaller head circumference and lower neuropsychological development level as compared with the full-term infants aged one year(all P<0.05).Weight at birth and feeding method were the influencing factors of abnormal development quotient of preterm infants(all P<0.05).Conclusion In comparison with the full-term infants,the preterm infants at corrected age of one year have retarded physical and neuropsychological development.For multiple factors might influence the neuropsychological development of the preterm infants,it is necessary to enhance follow-up monitoring of pre-term infants and to provide scientific intervention and guidance.