子宫内膜异位症及腺肌症患者阴道微生态临床分析

Clinical analysis of vaginal microecology in patients with endometriosis and adenomyosis

目的探讨子宫内膜异位症(内异症)及腺肌症患者阴道微生态和阴道菌群分布情况。方法选择内异症患者48例(内异症组),腺肌症患者54例(腺肌症组),健康志愿者30例(对照组)为研究对象。采用酶化学反应法检测3组受试者阴道分泌物的微生态状况及菌群分布情况,并对3组受试者阴道分泌物的清洁度、细胞类型、菌群密集度、菌群分布及微生态功能指标进行统计分析。结果3组受试者阴道菌群密集度、菌群多样性比较及阴道微生态功能指标Nugent评分、过氧化氢及pH值比较,差异均有统计学意义(均P<0.05)。结论内异症及腺肌症患者的阴道微生态环境相对更复杂。

Objective To explore the vaginal microecology and vaginal flora distribution in patients with endometriosis and adenomyosis.Methods Forty-eight patients with endometriosis(endometriosis group),54 with adenomyosis(adenomyosis group)and 30 healthy volunteers(control group)were enrolled as subjects.The enzyme chemical reaction test was employed to determine the microecological status and microflora distribution of vaginal secretions in the subjects of the three groups,and a statistical analysis of the cleanliness,cell type,microflora density,microflora distribution,and microecological function indicators of vaginal secretions of the subjects was performed in the three groups.Results There were statistically significant differences among the three groups in vaginal microflora density and diversity,and vaginal microecological function indicators of Nugent scores,hydrogen peroxide and pH value(all P<0.05).Conclusion Patients with endometriosis and adenomyosis exhibit more complex vaginal microecological environment.