经皮血管球囊成形术联合血管内支架植入术治疗外周动脉血管阻塞性疾病患者临床研究

Clinical Study of Percutaneous Balloon Angioplasty Combined with Endovascular Stenting in the Treatment of Patients with Peripheral Arterial Vascular Obstructive Disease

目的研究经皮血管球囊成形术联合血管内支架植入术治疗外周动脉血管阻塞性疾病患者的临床疗效。方法方便选取该院自2017年2月-2019年7月收治的89例外周动脉血管阻塞性疾病确诊患者作为研究对象,按治疗方法不同将其分为实验组和对照组,对照组(44例)采用溶栓常规方法治疗,实验组(45例)采用经皮血管球囊成形术联合血管内支架植入术治疗,比较两患者的血管再通情况、5 min行走的距离、踝肱指数(ABI)和并发症情况。结果实验组总再通率为95.5%,对照组总再通率75.0%,差异有统计学意义(χ^2=9.107,P=0.012)。实验组5min行走的距离(479.7±43.5)m高于对照组(329.6±22.7)m(t=23.297,P=0.003)。实验组踝肱指数为(0.88±0.73)高于对照组为(0.51±0.09)(t=3.214,P=0.002)。实验组2例患者出现并发症,并发症发生率为4.4%。对照组21例患者出现并发症,并发症发生率为45.5%,明显高于对照组(χ^2=13.985,P=0.001)。结论经皮血管球囊成形术联合血管内支架植入术治疗外周动脉血管阻塞性疾病患者安全有效,是一种疗效显著的治疗方式。

Objective To study the clinical efficacy of percutaneous balloon angioplasty combined with endovascular stenting in the treatment of patients with peripheral arterial vascular obstructive disease.Methods A total of 89 patients with confirmed peripheral arterial vascular obstructive disease admitted to the hospital from February 2017 to July 2019 were convenient enrolled.The patients were divided into experimental group and control group according to different treatment methods.The control group(44 cases)was treated with thrombolysis conventional methods.The experimental group(45 cases)was treated with percutaneous balloon angioplasty combined with endovascular stenting.The recanalization of the two patients,the distance of 5 minutes walking,and the ankle brachial index(ABI)and complications were compared.Results The total recanalization rate of the experimental group was 95.5%,and the total recanalization rate of the control group was 75.0%,the difference was statistically significant(χ^2=9.107,P=0.012).The distance traveled by the experimental group for 5 minutes(479.7±43.5)m was higher than that of the control group(329.6±22.7)m(t=23.297,P=0.003).The ankle brachial index of the experimental group was(0.88±0.73)higher than that of the control group(0.51±0.09)(t=3.214,P=0.002).Complications occurred in 2 patients in the experimental group,and the complication rate was 4.4%.Complications occurred in 21 patients in the control group,and the complication rate was 45.5%,which was significantly higher than that in the control group(χ^2=13.985,P=0.001).Conclusion Percutaneous balloon angioplasty combined with endovascular stenting is a safe and effective treatment for patients with peripheral arterial vascular obstructive disease.