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CA125、CK7、Ki67联合检测诊断卵巢癌的价值观察

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摘要 目的探讨糖类抗原125(CA125)、细胞角蛋白7(CK7)、增值细胞核抗原(Ki67)联合检测诊断卵巢癌的价值。方法将本院2018年5月~2019年5月收治的卵巢肿瘤患者85例作为观察组,其中包括41例卵巢恶性肿瘤患者与44例卵巢良性肿瘤患者,另外同时选取40例体检健康女性作为对照组。检测并比较两组患者入院后的CA125、CK7、Ki67水平,分析3种指标单独和联合检测对卵巢癌的诊断价值。结果恶性肿瘤组CA125(254±88.56)×10~3U/L,良性肿瘤组(45±9.47)×10~3U/L,对照组 (22±6.45) ×10~3U/L,组间差异有统计学意义(P<0.05);联合检测的敏感性、特异性、准确性、阳性预测值、阴性预测值均高于CA125、CK7、Ki67单项检测,差异均具有统计学意义(P<0.05)。结论 CA125、CK7和Ki67对卵巢癌的临床诊断有重要价值,是理想的卵巢癌诊断标记物,三者联合检测可有效增加卵巢癌的诊断可信度。
作者 冷茹冰
出处 《西藏医药》 2020年第2期32-34,共3页 Tibetan Medicine
关键词 CA125 CK7 Ki67卵巢癌
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