早期介入和保守疗法治疗急性非ST段抬高型心肌梗死的有效性和安全性对比

Effectiveness and safety of early intervention and conservative therapy in the treatment of acute non-ST segment elevation myocardial infarction

目的探讨对急性非ST段抬高型心肌梗死患者实施早期介入和保守疗法治疗的有效性和安全性。方法选取2017年1月至2018年10月本院急诊科收治的60例急性非ST段抬高型心肌梗死患者作为研究对象,根据患者实际情况分为介入组(n=30)和保守组(n=30),对介入组实施早期介入术治疗,对保守组实施早期保守疗法1周后再实施介入术治疗,比较两组患者疗效、心功能及远期预后状况。结果介入组总有效率高于保守组,差异有统计学意义(P<0.05);治疗后6个月,介入组左室射血分数高于保守组,左室收缩末内径、左室舒张末内径低于保守组,差异有统计学意义(P<0.05)。介入组出院后6个月内不良心血管事件总发生率低于保守组,差异有统计学意义(P<0.05)。结论急性非ST段抬高型心肌梗死患者实施早期介入治疗效果优于保守疗法,且可降低不良心血管事件风险,安全性高。

Objective To investigate the efficacy and safety of early intervention and conservative therapy in patients with acute non-ST-segment elevation myocardial infarction.Methods 60 cases of acute non-ST-segment elevation myocardial infarction from January 2017 to October 2018 in our hospital of emergency department were included in the study.According to the actual early treatment methods,the patients were divided into intervention group(n=30)and conservative group(n=30).The intervention group was treated with early interventional therapy.The conservative group was treated with early conservative therapy for one week before interventional therapy.The curative effect and cardiac function of the patients were analyzed.And the long-term prognosis.Results The total effective rate of intervention group was higher than that of conservative group(P<0.05).The left ventricular ejection fraction in intervention group was higher than that in conservative group 6 months after treatment,and the left ventricular end systolic diameter and left ventricular end diastolic diameter were lower than that in conservative group(P<0.05).The total incidence of adverse cardiovascular events within 6 months after discharge in intervention group was lower than that in conservative group(P<0.05).Conclusion Early interventional therapy is superior to conservative therapy in the treatment of acute non-ST-segment elevation myocardial infarction,and can reduce the risk of adverse cardiovascular events with high safety.