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Application of CRISPR/Cas-mediated base editing for directed protein evolution in plants 被引量:1

Application of CRISPR/Cas-mediated base editing for directed protein evolution in plants
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摘要 Breeding for improved cultivars of existing crops depends mainly on the available amount of genetic variability in yield or quality related genes.For thousands of years,humans have relied on naturally occurring mutations to recombine and select improved crops.Using chemical or physical mutagens,the amount and range of mutations could be increased,accelerating the development of new traits.Nevertheless,naturally occurring or randomly induced mutations lead to unpredictable breeding outcomes and therefore necessitate tedious rounds of backcrossing to eventually produce useful phenotypes(Pacher and Puchta,2017).
机构地区 Botanical Institute
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2020年第4期613-616,共4页 中国科学(生命科学英文版)
关键词 BREEDING CROPS CULTIVAR
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