非小细胞肺癌脑转移的治疗进展

Progress in the treatment of brain metastasis of non-small cell lung cancer

肺癌是发病率和死亡率很高的恶性肿瘤,其中非小细胞肺癌约占肺癌的80%,而且在疾病发展过程中易发生脑转移,一旦发生脑转移,严重影响患者的生存质量并危及生命。肺癌脑转移的治疗方法包括外科手术、化疗、全脑放射治疗、立体定向放射治疗、分子靶向治疗和免疫治疗等,治疗手段多种多样,治疗效果有差异,对于不同患者如何选择合理且有效的治疗方案是目前研究的热点之一。本文将对非小细胞肺癌脑转移相关进展进行综述,以期为肺癌脑转移患者选择更合理的临床治疗方案。

Lung cancer is a malignant tumor with high morbidity and mortality,in which non-small cell lung cancer accounts for about 80%of lung cancer,which affects the patient's quality of life and endangers life.The treatment methods of brain metastasis of lung cancer include surgery,chemotherapy,whole brain radiotherapy,stereotactic radiotherapy,molecular targeted therapy and immunotherapy.How to choose reasonable and effective treatment for different patients is one of the hot topics.This article will review the progress of NSCLC brain metastasis in order to choose more rational clinical treatment for lung cancer patients with brain metastasis.