2015年重庆市肿瘤登记地区宫颈癌疾病负担分析

Analysis on disease burden of cervical cancer in cancer registration sites,Chongqing municipality,2015

目的:了解2015年重庆市宫颈癌发病率、死亡率、伤残调整寿命年。方法:收集整理2015年重庆市11个肿瘤登记点报告的宫颈癌发病死亡病例(ICD-10编码为C53)。统计分析宫颈癌发病率、死亡率、标化发病率、标化死亡率、发病和死亡截缩率、发病或死亡累积危险度、早死所致的寿命损失年、残疾所致寿命损失年、伤残调整寿命年等指标。城市与农村宫颈癌发病率与死亡率的比较采用χ^2检验。结果:2015年重庆市肿瘤登记地区共报告宫颈癌新发病例916例,宫颈癌粗发病率为18.29/10^5,标化发病率为14.26/10^5,标化发病率农村(15.60/10^5)高于城市(12.32/10^5),差异有统计学意义(P<0.001)。2015年共报告宫颈癌死亡病例283例,粗死亡率为5.65/10^5,标化死亡率为3.98/10^5。2015年重庆市宫颈癌截缩发病率为32.60/10^5,截缩死亡率为8.32/105,发病率与死亡率累积危险度分别为1.41%与0.49%。宫颈癌导致的DALYs、YLDs和YLLs分别是6.76千人年、5.00千人年与1.76千人年。结论:重庆市宫颈癌发病率与死亡率高于全国平均水平,疾病负担重,疾病负担农村高于城市。

Objective:To investigate the incidence,mortality and disability adjusted life years of cervical cancer in Chongqing,2015.Methods:Cervical cancer cases(ICD-10:C53)reported from 11 cancer registration sites in Chongqing,2015 were collected and analyzed indicators including the incidence,mortality,age-standardized incidence rate by Chinese standard population(ASIRC),age-standardized mortality rate by Chinese standard population(ASMRC),truncated rate of incidence and mortality with age group 35~64 years old,cumulative risk of incidence and mortality,years of life lost with premature death(YLLs),years lived with disability(YLDs)and disability adjusted life years(DALYs).The difference of incidence and mortality between urban and rural area was compared by Chi-square test.Results:Total of 916 new diagnosis cases of cervical cancer cases were reported from 11 cancer registration sites,in Chongqing,2015.The crude incidence of cervical cancer was 18.29/10^5.ASIRC of cervical cancer was 14.26/10^5.ASIRC of cervical cancer in rural area(15.60/10^5)was higher than that in urban area(12.32/10^5)(P<0.001).283 death cases of cervical cancers were reported in 2015.And the crude mortality and ASWRC of cervical cancer was 5.65/10^5 and 3.98/10^5 respectively.The truncated rate of cervical cancer incidence and mortality of age group of 35~64 was 32.60/10^5 and 8.32/10^5 respectively.The cumulative risk of incidence and mortality of cervical cancer was 1.41%and 0.49%.DALYs,YLDs and YLLs were 6.76,5.00 and 1.76 years per thousand persons.Conclusion:The incidence and mortality of cervical cancer was higher than national average incidence and mortality of cervical cancer in Chongqing.The burden of disease of cervical cancer was high.The burden of disease of cervical cancer in rural area was higher than that in urban area.