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糖尿病对缺血性心脏病合并左心功能不全患者外科血运重建近中期疗效的影响 被引量:1

Influence of diabetes mellitus on short and mid-term outcomes of patients with ischemic heart failure undergoing surgical revascularization
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摘要 目的探讨糖尿病(DM)对缺血性心脏病合并左心功能不全患者外科血运重建近中期疗效的影响。方法收集2007年1月至2017年12月在本院接受冠状动脉旁路移植术治疗的缺血性心脏病合并左心功能不全患者的临床资料并完成2年随访,根据是否合并DM进行分组。比较两组在围术期复合终点事件及2年随访期间复合终点事件方面的差异。结果两组围术期复合终点事件(3.5%vs.0.6%,P=0.121)无显著差异,DM组术后2年随访复合终点事件显著高于非DM组(6.4%vs.0.6%,P=0.006)。结论对于缺血性心脏病合并左心功能不全患者,围术期积极的血糖管理可以明显降低住院期间DM可能引起的相关不良事件,但DM对该类患者近中期的不良影响在术后近中期即可显现,需在术后尽早对患者加强随访及干预。 Objective The aim of this study was to evaluate the effect of diabetes mellitus(DM)on the short and mid-term outcomes of surgical revascularization in patients with ischaemic heart failure.Methods Clinical data of patients with ischemic heart failure who underwent CABG in our hospital from January 2007 to December 2017 were collected.The patients were divided into two groups according to whether combined with DM or not to compare the difference of perioperative composite end point events and 2-year follow-up major adverse cardiovascular and cerebrovascular events Results There was no significant difference between DM group and non-DM group in perioperative composite end point events(3.5%vs.0.6%,P=0.121).However,the incidence of MACCE was sig nificantly higher in DM group than non-DM group(6.4%vs 0.6%,P=0.006)after two years.Conclusion With a strict periopera tive glucose management,DM did not significantly increase the perioperative risk in patients with ischemic heart failure.However,the mid-term outcome was significantly affected by DM.For this subgroup of patients,close postoperative follow-up and timely medical in tervention were needed.
作者 刘猛 张华军 成楠 吴远斌 王嵘 Liu Meng;Zhang Huajun;Cheng Nan;Wu Yuanbin;Wang Rong(Chinese PLA General Hospital,Beijing 100853,China)
出处 《中国体外循环杂志》 2020年第2期108-112,共5页 Chinese Journal of Extracorporeal Circulation
基金 军队保健专项项目编号(17BJZ31)。
关键词 缺血性心脏病 左心功能不全 糖尿病 冠状动脉旁路移植术 Ischemic heart disease Left ventricular dysfunction Diabetes mellitus Coronary artery bypass grafting
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