摘要
镁及镁合金因其适宜的腐蚀降解性能、优异的力学性能与生物学性能等,逐渐成为骨科内固定材料、口腔颌面外科骨修复材料、心脑血管支架材料等领域研究热点。本文从合金元素选择及镁合金力学性能、腐蚀降解性能、生物学性能等方面介绍国内外可降解镁合金生物材料研究现状,总结目前可降解生物镁合金材料设计、力学性能、腐蚀降解性能、细胞生物学性能和动物体内实验研究结果,展望可降解吸收生物镁合金材料亟待解决的科学问题及其应用前景。
Magnesium and its alloys have attracted a great attention in the fields of orthopedic implants,bone-repairing materials of maxillofacial surgery and cardiovascular stents because of their excellent mechanical properties,favorable degradation behavior and good biocompatibility.In the present work,the paper introduced the development of the biodegradable magnesium alloys through the selection of alloying elements,mechanical properties,degradation behavior and biological properties of bio-magnesium alloys.The paper also summarized the materials designing,mechanical properties,degradation behavior,cell biological performance and in vivo results of bio-magnesium alloys.Finally,the review has prospected the scientific questions which should be solved and applications of biodegradable magnesium alloys.
作者
彭泽惠
喻正文
刘建国
Peng Zehui;Yu Zhengwen;Liu Jianguo(School of Stomatology,Zunyi Medical University,Zunyi Guizhou 563099,China;Institution of Higher Education in Guizhou Province,The Key Laboratory of Oral Diseases Research of Zunyi City,Zunyi Guizhou 563099,China)
出处
《遵义医科大学学报》
2020年第1期125-130,共6页
Journal of Zunyi Medical University
基金
国家重点研发专项(NO:2016YFC1102800)
贵州省第六批人才基地《贵州省人才基地——医用生物材料研发》建设项目(NO:RCJD201909)
贵州省普通高等学校口腔疾病研究特色重点实验室开放课题(NO:SKLODR-2017-03)
遵义市科技局遵义医学院附属口腔医院市院联合基金重点项目(NO:遵市科合社字(2018)240)。
关键词
生物镁合金
力学性能
腐蚀降解性能
生物学性能
研究现状
biodegradable Mg-based alloy
mechanical properties
biodegradation behavior
biological performance
research status
