维持性血液透析患者疾病不确定感与抑郁、希望的关系研究

Study on the relationship between uncertainty in illness,depression and hope in patients with maintenance hemodialysis

目的探讨维持性血液透析患者疾病不确定感的现状及其与抑郁、希望的关系。方法采用一般资料调查表、疾病不确定感量表、抑郁自评量表、Herth希望量表,对符合纳入标准的180例维持性血液透析患者进行问卷调查。结果患者疾病不确定感总分为(74.23±7.64)分,抑郁总分为(53.04±9.59)分,希望总分为(32.33±3.05)分。疾病不确定感总分与抑郁总分呈正相关(r=0.429,P<0.001),与希望总分呈负相关(r=-0.348,P<0.001)。多元线性回归分析显示,患者抑郁水平对疾病不确定感有正向预测作用(β=0.170,P<0.001),希望水平对疾病不确定感有负向预测作用(β=-0.398,P<0.001)。结论维持性血液透析患者疾病不确定感处于较高水平,且与患者的抑郁、希望水平相关。

Objective To investigate the status of uncertainty in illness with maintenance hemodialysis(MHD)and its relationship with depression and hope.Methods Self-made questionnaire,Chinese version of Mishel disease uncertainty scale,depression self-rating scale,and Herth hope scale were used to investigate 180 MHD patients who met the inclusion criteria.Results The average total scores were 74.23±7.64 for Chinese version of Mishel disease uncertainty scale,53.04±9.59 for depression self-rating scale,and 32.33±3.05 for Herth hope scale.The total score of uncertainty in illness was positively correlated with the total score of depression(r=0.429,P<0.001),and was negatively correlated with the total score of hope(r=-0.348,P<0.001).Multiple linear regression analysis showed that the level of depression could positively predict the level of uncertainty in illness(β=0.170,P<0.001),and the level of hope could negatively predict the level of uncertainty in illness(β=-0.398,P<0.001).Conclusions MHD patients had a higher level of uncertainty in illness,which was related to the levels of depression and hope.