育龄女性阴道微生态失衡的影响因素分析

Analysis on influencing factors of vaginal microecological imbalance in childbearing age females

目的评估育龄女性阴道微生态失衡的影响因素。方法选取于该院放置吉尼致美节育器术后1、3、6个月来院复诊的妇女118例为研究对象,选取同期门诊健康体检的育龄女性120例为对照组,利用阴道微生态评价体系分析其阴道分泌物,并通过询问病史从生殖角度分析影响阴道微生态失衡的高危因素。结果观察组术后1、3、6个月阴道微生态失衡分别为32例(28.57%)、26例(22.03%)、21例(17.80%),各阶段微生态失衡率比较差异无统计学意义(P>0.05);对照组阴道微生态失衡21例(17.50%),观察组各阶段微生态失衡率分别与对照组比较均差异无统计学意义(P>0.05)。同时观察组微生态失衡不同分类,组内各阶段比较及分别与对照组比较均差异无统计学意义(P>0.05)。不同周性生活次数及人工流产次数,阴道微生态失衡发生率有明显差异(均P<0.05)。不同首次性生活年龄及避孕措施对阴道微生态失衡影响无明显差异(P>0.05)。Logistic多因素分析:每周性生活次数及人工流产次数是阴道微生态失衡的高危因素,OR(95%CI)分别是:2.654(1.578~4.466)、2.298(1.311~4.027)。结论性生活及人工流产次数是育龄女性阴道微生态失衡影响生殖的高危因素。

Objective To evaluate the influencing factors of vaginal microecological imbalance in females of childbearing age.Methods A total of 118 women subsequently visiting the hospital in 1,3,6 months after placing Gini-IUD were selected as the study subjects.Contemporaneous 120 women of childbearing age undergoing the healthy physical examination in the outpatient department were selected as the control group.The vaginal microecological evaluation system was used to analyze the vaginal secretions.Then the high risk factors affecting the vaginal micro-ecological imbalance were analyzed from the reproduction angle by inquiring the disease history.Results The vaginal micro-ecological imbalance in postoperative 1,3,6 months had 32 cases(28.57%),26 cases(22.03%)and 21 cases(17.80%)respectively.The micro-ecological imbalance rate had no statistical difference among different periods(P>0.05).There were 21 cases(17.50%)of vaginal micro-ecological imbalance in the control group.There was no statistically significant difference in the micro-ecological imbalance rate between the observation group and the control group(P>0.05).At the same time,the different classification of the micro-ecological imbalances had no statistical difference among the different intra-group stages and between the observation group and the control group(P>0.05).The micro-ecological imbalance rate had statistical difference among different weekly sexual life times and artificial abortion times(P<0.05).The influence of different first time sexual life age and contraception measures on the vaginal micro-ecological imbalance had no obvious difference(P>0.05).The Logistic multivariate analysis showed that the times of weekly sexual life and the times of artificial abortions were the high risk factors for vaginal microecological imbalance.The OR value and 95%CI confidence interval were 2.654(1.578-4.466),2.298(1.311-4.027).Conclusion The sexual life and times of artificial abortion are the high risk factors affecting reproduction in the childbearing age women with vaginal microecological imbalance.