大丽轮枝菌YMF1.02083的化学成分研究

Chemical Constituents of Verticillium dahliae YMF1.02083

从大丽轮枝菌(Verticillium dahliae)YMF1.02083发酵液的甲醇提取物中分离得到3个化合物。经质谱、核磁共振波谱分析,鉴定其为(9Z,11E,13E)-9,11,13-octadecatrienoic acid(Ⅰ)、4-hydroxy-benzene-ethanol(Ⅱ)和(3β,5α,6α,22E)-3-hydroxy-5,6-epoxy-7-one-8(14),22-dien-ergosta(Ⅲ);这3个化合物在浓度为200μg·mL^-1时,对秀丽隐杆线虫(Caenorhabditis elegans)均无毒杀活性。

We separated three compounds from methanol extract of Verticillium dahliae YMF1.02083 fermentation broth.Moreover,the three compounds are identified as(9Z,11E,13E)-9,11,13-octadecatrienoic acid(Ⅰ),4-hydroxy-benzene-ethanol(Ⅱ),and(3β,5α,6α,22E)-3-hydroxy-5,6-epoxy-7-one-8(14),22-dien-ergosta(Ⅲ)by MS and NMR spectra.When the concentrations of the three compounds are 200μg·mL^-1,they all have non-toxicity to Caenorhabditis elegans.