正常人群睡眠效率与BMI相关性的横断面研究

Cross-sectional study on the correlation between sleep efficiency and BMI in general population

目的基于多导睡眠图监测(polysomnography,PSG)研究客观的睡眠效率与体质指数(BMI)之间的关系。方法采用多导睡眠图对正常人群的睡眠效率、睡眠时间等指标进行监测;使用多元线性回归分析探索睡眠效率与BMI之间的关系。结果研究纳入2251名睡眠心脏健康研究的正常人群(1058名男性,1193名女性)。平均年龄(51.9±5.5)岁。与BMI正常的受试者相比,BMI较高人群睡眠效率较低。单因素线性回归分析显示,睡眠效率与BMI呈负相关(β-0.065,CI-0.091^-0.039;P<0.001)。校正年龄、性别、吸烟、高血压、糖尿病、胆固醇、三酰甘油、高密度脂蛋白和睡眠呼吸暂停指数后,睡眠效率与BMI呈负相关(β-0.034,CI-0.060^-0.008,P=0.012)。结论睡眠效率与BMI密切相关。睡眠效率可能是肥胖发生的预测因素,提高睡眠效率可能有助于预防肥胖的发生。

Objective To investigate the relationship between sleep efficiency and body mass index(BMI)through polysomnography(PSG).Methods Sleep efficiency,sleep duration and other indexes of general population were monitored and evaluated by using PSG.Sleep efficiency was defined as total wake-time/bedtime.Multiple linear regression analysis was used to explore the relationship between sleep efficiency and BMI.Results The study included 2,251 Sleep Heart Health Study(SHHS)patients(1058 males and 1193 females).The average age was 51.9±5.5 years.People with higher BMI had lower sleep efficiency than normal subjects.Univariate linear regression showed a negative correlation between sleep efficiency and BMI(β-0.065,CI-0.091 to-0.039;P<0.001).After adjustment for age,sex,smoking,high blood pressure,diabetes,cholesterol,triglycerides,HDL and sleep apnea index,there was a significant negative correlation between sleep efficiency and BMI(β-0.034,CI-0.060 to-0.008,P=0.012).Conclusion The results suggest that sleep efficiency is closely related to BMI.Sleep efficiency may be a predictor of obesity,and improving sleep efficiency may help prevent obesity.