非传染性输血不良反应与用血量、输血人次、输血品种的关系探讨

Study on the Relationship among the Adverse Reactions of Noncommunicable Blood Transfusion,Volume of Blood Supply,the Number of Patients with Transfusion and Varieties of Blood Transfusion

目的探讨本地区输血不良反应与用血量、输血人次、输血品种的关系。方法对146例输血不良反应进行回顾性调查,并对用血量、输血人次、人均输血量、血浆占比等指标进行相关性分析。结果输血不良反应发生率为0.20%(146/72054),其中,2015年与2014年、2018年与2017年比较,差异有统计学意义(P<0.05);过敏反应占54.11%(79/146),发热反应占39.73%(58/146),其他反应占6.16%(9/146);输注红细胞类、血浆类、红细胞类+血浆类成分引起过敏反应分别占16.45%、43.04%、40.51%,引起发热反应分别占70.69%、8.62%、20.69%;人均输血量3.6U,平均血浆占比49.08%。结论合理使用血液制品,降低临床用血血浆占比,可进一步减低本地区输血不良反应发生率。

Objective To explore the relationship among the adverse reactions of noncommunicable blood transfusion,volume of blood supply,the number of patients with transfusion and varieties of blood transfusion.Methods 146 Patients with adverse reactions of blood transfusion were investigated retrospectively,and correlation analysis was conducted on indicators such as volume of blood supply,the number of patients with transfusion,varieties of blood transfusion and plasma proportion.Results The incidence of adverse reactions to blood transfusion was 0.20%(146/72054),among which,the differences between 2015 and 2014,and between 2018 and 2017 were statistically significant(P<0.05).Anaphylaxis accounted for 54.11%(79/146),febrile reactions accounted for 39.73%(58/146),and other reactions accounted for 6.16%(9/146).Allergic reactions caused by infusion of erythrocyte,plasma,erythrocyte and plasma components accounted for 16.45%,43.04%and 40.51%,respectively.Meanwhile,the ratio of febrile reactions were 70.69%,8.62%and 20.69%,respectively.The average blood transfusion volume was 3.6 U and the average plasma proportion was 49.08%.Conclusion Reasonable selection of blood products and reducing the proportion of plasma in clinical blood transfusion can further reduce the incidence of adverse reactions in blood transfusion in this region.