酒精戒断综合征的临床效果分析

Clinical Effect Analysis of Alcohol Withdrawal Syndrome

目的研究患有酒精戒断综合征病人的临床表现,并就其治疗方法进行评价。方法任意抽选于2017年1月-2019年1月德宏州人民医院接收的36名患病病人,对其主要临床表现进行归纳总结。此外,将其随机分为观察组、对照组各18例。观察组病人使用阿普唑仑进行治疗,对照组病人使用地西泮进行治疗。观察记录两组病人的治疗有效率、HAMA、HAMD、SF-36评分及不良反应的发生情况。结果接受观察的患病病人在精神状态、胃肠道表现出了异常,主要临床症状表现为谵妄、抑郁、易激惹、腹泻、恶心呕吐。观察组病人治疗有效率、HAMA、HAMD、SF-36评分均优于对照组病人,且不良反应发生率低于对照组病人,差异均具有统计学意义(P<0.05)。结论酒精戒断综合征病人在精神、胃肠道方面表现出异常。经过阿普唑仑药物治疗后,相关的临床症状可以得到有效缓解,且相关不良反应也较少。

Objective To study the clinical manifestations of patients with alcohol withdrawal syndrome and evaluate the treatment.Methods 36 patients admitted to the Dehong People’s Hospital from January 2017 to January 2019 were randomly selected and were divided into the observation group and control group(n=18),patients in the observation group were treated with alprazolam and the control group were treated with diazepam.The main clinical manifestations of all patients were summarized,and The treatment efficiency,HAMA,HAMD,sf-36 score and the occurrence of adverse reactions of the two groups were observed and recorded.Results The patients under observation showed abnormal mental state and gastrointestinal tract,and the main clinical symptoms were delirium,depression,irritability,diarrhea,nausea and vomiting.HAMA,HAMD and sf-36 scores in the observation group were all better than those in the control group,and the incidence of adverse reactions was lower than those in the control group.The differences were statistically significant(P<0.05).Conclusion Patients with alcohol withdrawal syndrome may show mental and gastrointestinal abnormalities.After treatment with alprazolam,the related clinical symptoms can be relieved and there were fewer adverse reactions.