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沙丁胺醇联合布地奈德雾化吸入治疗小儿毛细支气管炎的临床效果观察 被引量:5

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摘要 目的观察沙丁胺醇联合布地奈德雾化吸入治疗小儿毛细支气管炎的临床效果。方法选取2017年2月-2019年5月江西省儿童医院收治的毛细支气管炎患儿62例为研究对象,随机分为观察组和对照组,每组31例。对照组给予布地奈德雾化吸入治疗,观察组在对照组基础上联合沙丁胺醇治疗。比较2组临床疗效、临床症状消失时间、炎性因子[白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、γ干扰素(IFN-γ)]水平以及不良反应。结果观察组总有效率为93.55%,高于对照组的70.97%(P<0.05);观察组咳嗽、憋喘、肺部啰音消失时间均短于对照组(P<0.01);治疗后,2组IL-6、TNF-α、IFN-γ水平均低于治疗前,且观察组优于对照组(P<0.01);2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论布地奈德联合沙丁胺醇雾化治疗小儿毛细支气管炎效果较好,可提高治疗有效率,缩短临床症状消失时间,降低炎性因子水平,且不良反应发生较少,用药安全性较高。
出处 《临床合理用药杂志》 2020年第8期83-84,共2页 Chinese Journal of Clinical Rational Drug Use
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