新生儿惊厥预后相关因素的研究进展

Progress in prognostic factors of neonatal seizures

惊厥是新生儿期常见的临床表现,常导致癫痫、脑性瘫痪、发育迟缓、智力障碍等严重的神经系统后遗症,甚至死亡。新生儿惊厥的病因繁多,是决定其预后的关键性因素。此外,个体因素差异、惊厥发作特点、脑电图表现等,均可不同程度影响惊厥患儿的预后。因此,早期病因诊断、及时发现可能预后不良者,并及时予以治疗,能有效改善新生儿惊厥预后、降低其死亡率。

Neonatal seizure is one of the most common manifestations of newborns,which could lead to severe neurological sequelae,such as epilepsy,cerebral palsy,developmental delay,mental retardation and even death.The causes of neonatal seizures are the key factors contributing to prognosis.In addition,individual factors,types of seizure and EEG could affect the prognosis in varying degrees.Therefore,for patients with poor prognosis,early diagnosis and treatment could effectively improve the prognosis and reduce the mortality.