Hypoxia in acute cardiac injury of coronavirus disease 2019:lesson learned from pathological studies

Coronavirus disease 2019(COVID-19)is an infectious respiratory disease caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which has infected 972,303 people and caused 50,322 deaths all over the world according to the latest WHO report.[1]As a highly contagious disease,COVID-19 has killed more people than severe acute respiratory syndrome(SARS)and middle east respiratory syndrome(MERS)combined,despite an relatively low case-fatality rate.[2,3]Although it mainly attacks respiratory system,other systems including cardiovascular system are also influenced by COVID-19.Acute cardiac injury(ACI)is also one of the noteworthy issues which researchers have noticed in several studies.[4–7] .