氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床效果

Clinical effect of amlodipine besylate and atorvastatin calcium tablets on hypertension with coronary heart disease

目的探讨氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床效果。方法将我院收治的164例高血压合并冠心病患者按治疗方式不同分为对照组(82例,硝苯地平缓释片)和观察组(82例,氨氯地平阿托伐他汀钙片)。比较两组的治疗效果。结果治疗后,两组的舒张压、收缩压、TC、TG、LDL-C、CPR、IL-12、ET水平均降低,HDL-C及NO水平均升高,且观察组优于对照组(P<0.05)。结论氨氯地平阿托伐他汀钙片能改善高血压合并冠心病患者的血压、血脂水平,降低血清炎性因子水平,保护血管内皮功能。

Objective To investigate the clinical effect of amlodipine besylate and atorvastatin calcium tablets on hypertension with coronary heart disease.Methods A total of 164 patients with hypertension and coronary heart disease treated in our hospital were divided into control group(82 cases,nifedipine sustained release tablets)and observation group(82 cases,amlodipine besylate and atorvastatin calcium tablets)according to different treatment methods.The treatment effects of both groups were compared.Results After treatment,diastolic pressure,systolic pressure,the levels of TC,TG,LDL-C,CPR,IL-12 and ET of both groups decreased,while the levels of HDL-C and NO increased,and those of the observation group were better than the control group(P<0.05).Conclusion Amlodipine besylate and atorvastatin calcium tablets can improve the blood pressure and blood lipid levels of patients with hypertension and coronary heart disease,reduce the levels of serum inflammatory factors,and protect vascular endothelial function.