摘要
2019年12月以来,新型冠状病毒(严重急性呼吸综合征冠状病毒2,SARS-CoV-2)感染在武汉暴发。近期不断有专家指出SARS-CoV-2感染者病情的突然加重可能和“炎症风暴”(细胞因子风暴)有关。但目前并无针对于此的特效药。笔者结合相关文献的检索和分析,对细胞因子风暴进行解读,对细胞因子风暴的药物治疗进行探索性综述,以期为临床治疗提供参考。
Novel coronavirus 2019(SARS-CoV-2)infection outbreak has occurred in Wuhan since December 2019.Cytokine storm(inflammatory factor storm)was suggested to be involved in the sudden deterioration of some SARS-CoV-2 infectors in the recent reports.However,no medicine was specific to the treatment of cytokine storm so far.This paper summarized the mechanism and potential therapeutic drugs of cytokine storm based on literature review and analysis,so as to provide references for the treatment of SARS-CoV-2.
作者
张竞文
胡欣
金鹏飞
ZHANG Jing-wen;HU Xin;JIN Peng-fei(Department of Pharmacy Administration and Clinical Pharmacy,School of Pharmaceutical Science,Peking University,Beijing 100191,China;Department of Pharmaceutical Science,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Science,Beijing Key Laboratory of Drug Clinical Risk and Personalized Medication Evaluation,Beijing 100730,China)
出处
《中国药学杂志》
CAS
CSCD
北大核心
2020年第5期333-336,共4页
Chinese Pharmaceutical Journal
