3.0T磁共振无对比剂冠状动脉血管成像的可行性

Feasibility of Non-contrast-enhanced Coronary Magnetic Resonance Angiography at 3.0T

目的探讨3.0T磁共振无对比剂冠状动脉血管成像的可行性及其图像质量影响因素。方法共纳入36例志愿者及24例可疑冠心病患者在3.0T磁共振行无对比剂冠状动脉磁共振血管成像,以冠状动脉节段为单位进行主观图像质量评分并将其分为图像质量合格组和不合格组,对比两组年龄、体质量指数(BMI)、心率、呼吸末膈肌位移及自由呼吸膈肌运动幅度。结果冠状动脉3支血管各节段图像质量评分均在2分以上,左前降支近中段图像质量高于其远段(P=0.000),左回旋支近段图像质量评分高于其远段(P=0.000),右冠状动脉近段图像质量评分高于其远段(P=0.001)。3.0T磁共振无对比剂冠状动脉图像质量合格为38例(64.4%)。图像质量合格组的BMI[(24.72±3.33)kg/m^2]、心率[(66.35±9.39)次/min]均低于图像质量不合格组的BMI[(27.82±3.61)kg/m^2](P=0.002)、心率[(75.32±11.67)次/min](P=0.002)。图像质量合格组的呼吸末膈肌位移[(4.43±2.07)mm]低于图像质量不合格组[(9.26±7.62)mm](P=0.013)。图像质量合格组的自由呼吸膈肌运动幅度[(21.35±6.02)mm]低于不合格组[(30.68±14.20)mm](P=0.012)。结论在成像质量方面,3.0T磁共振无对比剂磁共振血管成像可适用于冠状动脉血管成像,未来可以通过控制心率及呼吸因素进一步优化图像质量。

Objective To evaluate the feasibility of non-contrast-enhanced magnetic resonance angiography(NCE-MRA)on a 3.0T scanner.Methods Totally 36 volunteers and 24 patients with clinically suspected coronary artery disease underwent NCE-MRA.The quality of the NCE-MRA images was graded for each segment on a four-point scale.The subjects were divided into two groups according to image quality.The age,body mass index(BMI),heart rate,end-expiratory diaphragm displacement,and respiratory diaphragm motion amplitude were evaluated and compared.Results The average image quality score of every segment was above 2 points.The proximal and middle segments of left anterior descending artery had significantly higher quality scores than the distal segments(P=0.000)and the proximal segment of left circumflex coronary artery had significantly higher quality scores than the distal segments(P=0.000),the proximal segment of right coronary artery also had a significant higher quality score than its distal segment(P=0.001).The image quality was good in 38 subjects(64.4%).The heart rate[(66.35±9.39)beat/min vs.(75.32±11.67)beat/min](P=0.002)and the body mass index[(24.72±3.33)kg/m^2 vs.(27.82±3.61)kg/m^2](P=0.002)were significantly different between the good image quality group and the poor image quality group.The end-expiratory diaphragm displacement in good image quality group was(4.43±2.07)mm,which was significantly lower than that in poor image quality group[(9.26±7.62)mm](P=0.013).The respiratory diaphragm motion amplitude[(21.35±6.02)mm]in good image quality group was significantly lower than that in poor image quality group[(30.68±14.20)mm](P=0.012).Conclusion NCE-MRA on 3.0T is a feasible tool for visualization of the proximal and middle segments of coronary arteries,and the image quality can be optimized by controlling heart rate and respiration in the future.