麦冬水提物对运动小鼠耐力的影响

Effect of ophiopogon japonicus water extract on endurance of exercise mice

目的研究麦冬水提物对运动小鼠耐力作用的影响。方法通过小鼠负重游泳试验、爬杆试验、转棒试验及疲劳仪试验,研究25、50、150 mg/kg BW d各剂量组对运动小鼠耐力的影响。结果与阴性对照组比较,麦冬水提物高剂量组和中剂量组均能明显延长小鼠负重游泳时间,差异有统计学意义(F值分别为22.335和10.391,均P<0.01);麦冬水提物的高、中剂量组也能使小鼠爬杆时间、转棒时间、致疲劳不动时的时间及奔跑距离明显延长,差异有统计学意义(均P<0.05)。结论麦冬水提物可提高运动小鼠的耐力,有明显的抗运动疲劳作用。

Objective To study the effect of ophiopogon japonicus water extract on endurance of exercise mice.Methods The effects of 25,50,150 mg/kg bw d on endurance of exercise mice were studied by weight-bearing swimming test,climbing test,rotating test and fatigue test.Results Compared with the negative control group,the high and medium dose groups of ophiopogon japonicus water extract can obviously prolong the weight-bearing swimming time of mice,with F values of 22.335 and 10.391 respectively,and P values of less than 0.01;the high and medium dose groups of ophiopogon japonicus water extract can also significantly prolong the climbing time,rotating time,fatigue-induced immobility time and running distance of mice.Conclusion Ophiopogon japonicus water extract can improve the endurance of exercise mice and has obvious anti-exercise fatigue effect.