低FODMAP饮食对溃疡性结肠炎患者肠易激综合征样症状的影响

Effects of Low FODMAP Diet on IBS-Like Symptoms in Patients with Ulcerative Colitis

目的探讨低可酵解的低聚糖、双糖、单糖和多元醇(FODMAP)饮食对溃疡性结肠炎(UC)患者肠易激综合征(IBS)样症状的影响。方法以2018年6—12月在郑州大学第一附属医院门诊就诊的80例具有IBS样症状的UC患者为研究对象。在维持原有治疗不变的基础上,患者接受低FODMAP饮食治疗。观察低FODMAP饮食前、治疗6周后及回添FODMAP饮食2周后患者IBS症状量表(IBS-SSS)、焦虑自评量表(SAS)、抑郁自评量表(SDS)及IBS生活质量量表(IBS-QOL)评分情况。结果接受低FODMAP饮食后患者IBS样症状缓解,焦虑抑郁状态改善,生活质量提高。重新引入FODMAP饮食后,仍可维持IBS样症状缓解。结论低FODMAP饮食可有效改善UC患者IBS样症状。

Objective To investigate the effects of low fermentable oligosaccharides,disaccharides,monosaccharides and polyols(FODMAP)diet on irritable bowel syndrome(IBS)-like symptoms in patients with ulcerative colitis(UC).Methods Eighty UC patients with IBS-like symptoms who were treated in the First Affiliated Hospital of Zhengzhou University from June to December 2018 were included in the study.On the basis of original treatment,the patients start to eat low FODMAP diet.IBS symptom severity scale(IBS-SSS),self-rating anxiety scale(SAS),self-rating depression scale(SDS),and IBS-specific quality of life(IBS-QOL)scores before low FODMAP diet,6 weeks after treatment,and 2 weeks after adding FODMAP diet were observed.Results After low FODMAP diet,patients'IBS-like symptoms were relieved,anxiety and depression were reduced,and quality of life was improved.Reintroduction of FODMAP diet still maintains remission of IBS-like symptoms.Conclusion A low FODMAP diet could effectively alleviate IBS-like symptoms in UC patients.