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美法仑片联合硼替佐米和地塞米松治疗多发性骨髓瘤的临床效果 被引量:3

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摘要 目的观察美法仑片联合硼替佐米、地塞米松治疗多发性骨髓瘤(MM)的效果。方法选取郑州颐和医院2014年6月至2019年6月收治的70例MM患者,根据治疗方案分组,各35例。对照组接受VD方案(硼替佐米+地塞米松)治疗,观察组于对照组基础上加用美法仑片。对比两组疗效、不良反应及治疗前后血清增殖诱导配体(APRIL)、M蛋白水平。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,两组血清APRIL、M蛋白水平均较前降低,观察组血清APRIL、M蛋白水平低于对照组,差异有统计学意义(均P<0.05)。两组不良反应发生率差异无统计学意义(P>0.05)。结论美法仑片联合硼替佐米、地塞米松可有效提高MM疗效,降低患者血清APRIL、M蛋白水平。
出处 《河南医学研究》 CAS 2020年第11期2013-2014,共2页 Henan Medical Research
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