中药复方舒肤膏质量标准研究

Study on quality standard of Chinese medicine compound shufu cream

采用薄层色谱法对荆芥、防风、凌霄花和狼毒进行定性鉴别,采用高效液相色谱法对中药复方舒肤膏的有效成分梣酮和黄柏酮进行含量测定。结果表明,薄层色谱法结果理想,阴性样品无干扰;在5.92~47.36μg/mL梣酮与峰面积线性关系良好(r=0.999 1),平均回收率为99.76%(RSD=1.34%),在10.2~81.6μg/mL黄柏酮与峰面积线性关系良好(r=0.999 0),平均回收率为99.89%(RSD=1.63%),表明该方法操作简便,专属性好,准确可靠,可用于中药复方舒肤膏的质量控制。

TLC was used to qualitatively identify Nepeta cataria L, Saposhnikovia divaricata(Trucz.) Schischk, Campsis grandiflora and Euphorbia fischeriana Steud. The content of the active constituents of fraxinellone and obacunone from cortex dictamni was determined by HPLC. The results of TLC were ideal, and the negative samples had no interference. The linear relationship between the anthrone and the peak area was good(r=0.999 1) and the average recovery was 99.76%(RSD=1.34%) in the concentration range of 5.92~47.36 μg/mL. In the concentration range of 10.2~81.6 μg/mL, the linear relationship between the ketone and the peak area was good(r=0.999 0), and the average recovery was 99.89%(RSD=1.63%). This method is easy to operate, has good specificity, accurate and reliable, and can be used for quality control of traditional Chinese medicine compound skin cream.