肠道菌群对白血病影响的研究进展

Research progress in effects of intestinal microbiota on leukemia

人体肠道内存在大量微生物,研究发现,肠道菌群与白血病之间存在相互作用。白血病患者体内存在肠道菌群数量减少及菌群失调;而肠道菌群紊乱又会直接或通过免疫调控间接影响白血病的进展。解析肠道菌群与白血病之间的关系,为白血病的肠道菌群诊断提供关键目标,可以为改善疗效和预后提供新的策略。

There are a large number of microorganisms in human intestine.It has been reported that intestinal microbiota is corre-lated with leukemia.The decreased number of intestinal microbiota and dysbacteriosis are present in leukemia patients.The disorder of intestinal microbiota can directly influence the progress of the leukemia,indirectly through immune regulation.Exploration of the relationship between intestinal microbiota and leukemia would provide a key objective for the diagnosis of leukemia intestinal microbiota,and also supply new strategies for improving therapeutic effect and prognosis.