脓毒症相关性脑病的预后与康复

Prognosis and rehabilitation of sepsis-associated encephalopathy

脓毒症相关性脑病(SAE)是脓毒症的严重并发症,大大增加了脓毒症患者的病死率,此外,SAE的幸存者可能表现出长期的认知功能障碍,在危重症领域受到越来越多的关注。但关于SAE不良预后的机制及可能的预测指标,目前研究较少;而关于其康复手段,目前尚无针对性的方法报道。现就SAE的预后及康复的研究进展作一介绍,以期为临床儿童严重脓毒症的远期预后及康复治疗提供参考。

Sepsis-associated encephalopathy(SAE)is a serious complication of sepsis,which can greatly increase the mortality of patients with sepsis,and may result in prolonged cognitive dysfunction in SAE survivors.Therefore SAE has received more and more attention in the field of critical illness.However,there are few studies on the mechanism of poor prognosis and possible predictors of SAE,and no specific rehabilitation methods have been reported.In this article,progress in the research on the prognosis and rehabilitation of SAE is summarized,in order to provide a reference for the long-term prognosis and rehabilitation treatment of severe sepsis in children.