大肠埃希菌与儿科感染性疾病的研究进展

Advances in research on Escherichia coli and pediatric infectious diseases

大肠埃希菌是人体内常见的肠道定植菌,一定条件下可转变为致病菌引起感染性腹泻,少数情况可引起肠道外感染,如细菌性脑膜炎、下呼吸道感染、胆道感染、泌尿道感染等疾病。随着抗生素滥用现象的增多,大肠埃希菌参与不同感染性疾病的致病机制有其各自的特点。现就不同感染性疾病的危害、发病机制及治疗进展予以综述。

Escherichia coli is a common intestinal colonization bacterium in human body.It causes infectious diarrhea if it turns into a pathogenic bacterium under certain conditions.In a few cases,it can cause extraintestinal infections,such as bacterial meningitis,lower respiratory tract infection,biliary tract infection,and urinary tract infection,etc.With the increasing of antibiotic abuse,the pathogenesis of Escherichia coli in different infectious diseases has its own characteristics.The hazards,pathogenesis and treatment progress of different infectious diseases were reviewed in this paper.