摘要
目的构建肺癌患者施行单孔VATS术后发生切口愈合不良的风险预测模型。方法回顾性分析2017年1月~2019年6月期间笔者医院收治的120例施行单孔VATS手术的肺癌患者的资料。根据是否发生术后切口愈合不良将患者分为病例组(n=19)和对照组(n=101)。结合性别、年龄、营养状况、高血压、糖尿病、拔除胸管时间、TNM分期、病理类型等8项因素进行单因素分析及Logistic回归分析。结果单因素结果显示,年龄、营养状况、糖尿病、拔除胸管时间等观察指标与发生手术切口愈合不良有关(P<0.05)。Logistic回归分析结果显示,年龄(OR=6.902,95%CI:1.358~35.071,P=0.020),营养状况(OR=3.698,95%CI:1.136~12.035,P=0.030),糖尿病(OR=5.946,95%CI:1.815~19.475,P=0.003)是肺癌患者行单孔VATS术后发生切口愈合不良的独立危险因素。构建模型的ROC曲线下面积为0.843,回归模型结果可靠。结论年龄、营养状况、糖尿病是肺癌患者行单孔VATS术后发生切口愈合不良的独立危险因素,在临床上更应加以关注,以期减少切口愈合不良的发生率。
Objective To establish a risk prediction model for poor incision healing in patients with lung cancer after single-port VATS.Methods A total of 120 cases of patients with lung cancer after single-port VATS,which were analyzed retrospectively from January 2017 to June 2019 in our hospital,were divided into case group(n=19)and control group(n=101)according to whether poor incision healing occurred.Univariate analysis and Logistic regression analysis were performed based on 8 factors,including gender,age,nutritional status,hypertension,diabetes,chest tube removal time,TNM stage,pathological type.Results The results of univariate analysis showed that age,nutritional status,diabetes and chest tube removal time were associated with poor incision healing(P<0.05).Logistic regression analysis showed that age(OR=6.902,95%CI:1.358-35.071,P=0.020),nutritional status,(OR=3.698,95%CI:1.136-12.035,P=0.030)and diabetes(OR=5.946,95%CI:1.815-19.475,P=0.003)were the independent risk factors for poor incision healing in patients with lung cancer after single-port VATS.The area under the model ROC curve was 0.843,and the regression model was reliable.Conclusion Age,nutritional status,and diabetes were the independent risk factors for poor incision healing in patients with lung cancer after single-port VATS.More attention should be paid to these factors in order to reduce the incidence of poor incision healing.
作者
戴春雷
吕彦天
单月宏
彭勇
谢永明
臧蔚
Dai Chunlei;Lyu Yantian;Shan Yuehong(Department of Thoracic Surgery,Nanjing Medical University Affiliated Suzhou Hospital,Jiangsu 215000,China)
出处
《医学研究杂志》
2020年第4期149-152,共4页
Journal of Medical Research
基金
江苏省苏州市“科教兴卫”青年科技项目(kjxw2018027)。