不同剂量阿托伐他汀治疗冠心病临床效果探讨

The Clinical Effect of Different Doses of Atorvastatin on Coronary Heart Disease

为探讨不同剂量的阿托伐他汀药物对冠心病患者的治疗效果情况,提升临床治疗疗效,选取2018年4月-2019年4月前往我院治疗的98位冠心病患者为实验研究对象,随患者及家属意愿分为对照组与研究组,每组49人。对照组给予小剂量药物,研究组给予大剂量药物,比较临床效果。治疗前,不同剂量药物治疗前后患者血脂水平无显著差异(P>0.05);治疗后,不同剂量药物治疗前后患者血脂水平差异显著(P<0.05),研究组患者血脂水平显著优于对照组;两组不同剂量药物临床治疗有效率差异较大(P<0.05),研究组有效95.91%显著高于对照组有效77.55%。说明在临床治疗冠心病患者的工作中,使用大剂量阿托伐他汀进行治疗,临床治疗效果显著,可有效改善患者病情,不良反应较少,患者临床治疗满意度较高,有效降低医患纠纷的发生,临床可广泛应用并推广此方法。

In order to explore the therapeutic effect of different doses of atorvastatin on patients with coronary heart disease and improve the clinical therapeutic effect,98 patients with coronary heart disease who were treated in our hospital from April 2018 to April 2019 were selected as experimental research objects,and with the consent of the patients and their families,they were divided into a control group and a research group,with 49 people in each group.The control group was given low-dose drugs while the research group with high-dose drugs to compare clinical effects.Before treatment,there was no significant difference in blood lipid levels before and after treated with different doses of drugs(P>0.05);but after treatment,there was a significant difference in blood lipid levels(P<0.05),the blood lipid levels of the study group were significantly better than the control group;The two groups of different doses of drugs have significant differences in clinical treatment efficiency(P<0.05).The effective rate in the study group was 95.91%,which was significantly higher than that in the control group,77.55%.