探讨82例婴幼儿肺炎支原体感染的临床特点及治疗

Clinical Characteristics and Treatment of Mycoplasma Pneumoniae Infection in 82 Infants

目的探究婴幼儿肺炎支原体感染的临床特点及治疗手段。方法选取本院2017年5月至2018年4月收治的82例婴幼儿肺炎支原体感染的患儿,对其临床表现及体征、实验室检查、影像学表现等特点进行统计分析,同时对该疾病的治疗方法进行研究。结果肺炎支原体感染的患儿临床表现包括发热、咳嗽、喘息、肺部显著湿啰音;其中,82例患儿均出现不同程度的咳嗽症状,63例患儿出现发热症状,75例患儿肺部可闻及不同程度的湿啰音,28例患儿听诊出现喘鸣音,6例患儿出现如恶心呕吐等消化道症状。实验室检查方面,所有患儿血清肺支MP-IgM定性结果均为阳性,且MP-IgG定量检查均出现显著升高,多数患儿血常规显示白细胞计数显著增高,中性粒细胞超过50%,且C反应蛋白明显增高。影像学方面,所有患儿肺部均出现斑片状阴影。82例患儿经静滴阿奇霉素和糖皮质激素雾化治疗后,症状均明显好转,且后续随访显示均未出现复发病例。结论临床上婴幼儿肺炎支原体感染率较高,且临床表现不典型,故诊断时应与实验室检查、影像学表现紧密结合。婴幼儿肺炎支原体感染经阿奇霉素静滴和糖皮质激素治疗后,效果显著。

Objective To explore the clinical characteristics and treatment of infantile Mycoplasma pneumoniae infection.Methods 82 cases of infantile Mycoplasma pneumoniae infection in our hospital from May 2017 to April 2018 were selected.The clinical manifestations,physical signs,laboratory examination,imaging findings and other characteristics were analyzed statistically.Meanwhile,the treatment methods of the disease were studied.Results The clinical manifestations of children with Mycoplasma pneumoniae infection included fever,cough,wheezing,and significant lung moist rales.Among them,82 children had cough symptoms of varying degrees,63 children had fever symptoms,75 children had lung moist rales of varying degrees,28 children had wheezing in auscultation,and 6 children had lung moist rales.Gastrointestinal symptoms such as nausea and vomiting appear.In laboratory tests,all the children’s serum MP-IgM qualitative results were positive,and MP-IgG quantitative tests were significantly increased,most of the children’s blood routine showed a significant increase in white blood cell count,neutrophils more than 50%,and C-reactive protein significantly increased.In imaging,all children had patchy shadows in their lungs.After intravenous drip of azithromycin and glucocorticoid atomization,the symptoms of 82 children were significantly improved,and follow-up showed no recurrence.Conclusion Infant Mycoplasma pneumoniae infection rate is high in clinic,and the clinical manifestations are atypical,so the diagnosis should be closely combined with laboratory examination and imaging findings.Infantile Mycoplasma pneumoniae infection after azithromycin intravenous drip and glucocorticoid treatment,the effect is remarkable.