纤支镜肺泡灌洗术治疗小儿难治性肺炎支原体肺炎合并肺部大片病灶的临床效果

Clinical effect of bronchoalveolar lavage with fibrobronchoscope on refractory mycoplasma pneumoniae pneumonia complicated with large pulmonary lesions in children

目的探讨纤支镜肺泡灌洗术治疗小儿难治性肺炎支原体肺炎(RMPP)合并肺部大片病灶的临床效果。方法选取茂名市妇幼保健院2015年2月-2018年8月收治的RMPP合并肺部大片病灶患儿70例,采用随机数字表法分为参照组与试验组,各35例。参照组给予阿奇霉素联合甲泼尼龙治疗,试验组在参照组基础上给予纤支镜肺泡灌洗术治疗。比较两组临床效果,症状改善时间(体温恢复正常时间、肺部啰音消失时间、咳嗽消失时间),并观察两组不良反应和并发症发生情况。结果试验组治疗总有效率高于参照组,体温恢复正常时间、肺部啰音消失时间、咳嗽消失时间短于参照组(P<0.05)。两组不良反应和并发症发生率比较,差异无统计学意义(P>0.05)。结论纤支镜肺泡灌洗术治疗小儿RMPP合并肺部大片病灶的临床效果确切,可有效改善患儿临床症状,缩短治疗时间,且安全性较高。

Objective To explore the clinical effect of bronchoalveolar lavage with fibrobronchoscope on refractory mycoplasma pneumoniae pneumonia(RMPP) complicated with large pulmonary lesions in children.Methods A total of 70 cases of Children with RMPP complicated with large pulmonary lesions were selected from February 2015 to August 2018 in Maoming Maternal and Child Health Hospital,which were divided into reference group and test group according to the random number table method,35 cases in each group.The reference group was treated with azithromycin combined with methylprednisolone,the test group was treated with bronchoalveolar lavage with fibrobronchoscope on the basis of the reference group.Clinical effect,time for symptom improvement(time for body temperature to return to normal,time for lung rales to disappear,time for cough to disappear) were compared between the two groups,and the incidence of adverse reactions and copmlications were observed.Results The test group of total effective rate treatment was higher than reference group,and the time for body temperature to return to normal,lung rales to disappear,cough to disappear were shorter than reference group(P<0.05).There was no significant difference in the incidence rate of adverse reactions and copmlications between the two groups(P>0.05).Conclusion Bronchoalveolar lavage with fibrobronchoscope have an exact clinical effect for RMPP complicated with large pulmonary lesions in children,which can effectively improve the clinical symptoms of children,shorten the treatment time,and with high safety.