脑室外引流术后感染高危因素的临床分析

Clinical analysis of risk factors for infection in external ventricular drain

目的:分析脑室外引流术后与感染相关的危险因素。方法:回顾性分析2011年1月—2014年6月收治的98例脑室外引流患者的临床资料。结果:98例患者共实施了105次脑室外引流术,并放置脑室外引流管712 d。颅内感染的发生率为19.4%,每次手术操作的感染率为18.1%,每放置导管1000 d的感染率为26.7%。75.0%的颅内感染是由革兰阴性杆菌引起。74.5%的患者接受了抗生素预防治疗。颅内感染率随着住院时间的延长而增加。导管放置时间的延长会增加颅内感染的发生率。结论:在临猗县人民医院脑室外引流术后感染发生率较高,革兰阴性杆菌是最常见的感染菌。导管放置时间的延长会增加颅内感染的发生率。导管放置时间是颅内感染独立危险因素。

Objective:To analyze the risk factors of infection associated with external ventricular drain.Methods:Retrospective analysis of clinical data of 98 external ventricular drain patients from January 2011 to June 2014.Results:A total of 98 patients underwent 105 external ventricular drain procedures and 712 external ventricular drain catheter-days.The incidence of intracranial infection was 19.4%,the infection rate was 18.1%per procedure,and the drain-associated infection rate was 26.7%per 1000 catheter-days.75.0%of the infections were caused by Gram-negative micro-organisms.74.5%of patients received antibiotic prophylaxis.The infection rate increased with length of the hospital stay.The duration of catheterization was an independent risk factor related to intracranial infection.Conclusion:The rates of external ventricular drain-related infection are high in our hospital,Gram-negative micro-organisms were the most frequent agent.The length of time that the catheter was in place was an independent risk factor associated with infection.