儿童家族性渗出性玻璃体视网膜病变的荧光素眼底血管造影分析

Fluorescein fundus angiography in children with familial exudative vitreoretinopathy

目的观察并探讨家族性渗出性玻璃体视网膜病变(FEVR)的荧光素眼底血管造影(FFA)特征,分析其临床应用的优越性。方法选取2019年1月至2019年6月在我院确诊的FEVR患儿10例(20只眼)为研究对象,进行FFA检查。结果FEVR 1期9只眼(45.00%);2期6只眼(30.00%),3期3只眼(15.00%),4期2只眼(10.00%)。眼底检查可见后极部血管僵直,颞侧周边网膜血管分支增多、走形长。FFA检查可见周边血管呈柳枝样形态,荧光渗漏,伴有无血管区,新生血管呈团状高荧光。结论FFA是诊断FEVR的重要检查方法,能明确病变范围及指导临床治疗。

Objective To observe and assess the characteristics of fluorescein fundus angiography(FFA)in children with familial exudative vitreoretinopathy(FEVR)and to analyze its advantages in clinical application.Methods Ten children(20 eyes)with FEVR who were diagnosed in our hospital from January 2019 to June 2019 were selected as the subjects for fundus fluorescein angiography(FFA).Results Of the included children,9 eyes(45.00%)were in phase 1,6 eyes(30.00%)were in phase 2,3 eyes(15.00%)were in phase 3 and 2 eyes(10.00%)were in phase 4 of FEVR.Fundus examination showed that the retinal vessels near the posterior pole were stiff,while the number of branches and length of the peritemporal retinal vessels increased.FFA examination showed that the peripheral retinal vessels were willow-like in shape,with fluorescence leakage and non-vascular areas,and neovascularization was clustered with high fluorescence.Conclusions FFA is an important diagnostic method for FEVR,which could define the extent of lesion and guide clinical treatment.