摘要
提出一种光透过散射介质的散斑恢复算法,可实现大视场任意位置的聚焦。通过仿真模拟光路测量散射介质的传输矩阵并进行二值化处理,再利用数字微镜器件对入射光进行二值振幅调制,实现透过散射介质的单点或多点聚焦。由于不同聚焦位置的独立性,所提算法能够实现大视场任意位置聚焦。仿真结果表明:聚焦位置的光强增强因子随着采样数目的增加而增加;与传统三步相移法相比,在采样数目减少1/3的情况下,所提算法能够获得55%的增强比,比三步相移法高12%。所提算法对透过散射介质实现大视场范围扫描聚焦有重要意义,在生物医学成像领域具有广阔应用前景。
In this paper,a speckle recovery algorithm for light through scattering media that can achieve focusing at any position in a large field of view is proposed.The transmission matrix of the scattering medium is measured and binarized by simulating the optical path,and the digital micro-mirror device is used to modulate the binary amplitude of the incident light to achieve single-point or multi-point focusing through the scattering medium.Due to the independence of different focus positions,the algorithm can achieve large field-of-view focusing at any position.The simulation results show that the intensity enhancement factor of the focus position increases with the increase in the sampling number.Compared with the traditional three-step phase shift method,an enhancement ratio of 55%can be obtained by the proposed algorithm when the number of sampling is reduced by 1/3,which is 12%higher than that by the three-step phase shift method.The proposed algorithm exhibits great significance for realizing large field-of-view scanning and focusing through the scattering medium,making it applicable in the field of biomedical imaging.
作者
斯科
汤黎明
杜吉超
吴晨雪
徐晓滨
胡乐佳
陈佳佳
龚薇
Si Ke;Tang Liming;Du Jichao;Wu Chenxue;Xu Xiaobin;Hu Lejia;Chen Jiajia;Gong Wei(State Key Laboratory of Modern Optical Instrumentation,Department of Neurobiology,the First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,Zhejiang 310058,China;College of Optical Science and Engineering,Zhejiang University,Hangzhou,Zhejiang 310027,China;School of Brain Science and Brain Medicine,Zhejiang University,Hangzhou,Zhejiang 310058,China)
出处
《中国激光》
EI
CAS
CSCD
北大核心
2020年第2期394-400,共7页
Chinese Journal of Lasers
基金
国家自然科学基金(81771877,61975178)
浙江省自然科学基金(LZ17F050001,LR20F050002)。
关键词
生物光学
散射
传输矩阵
贝叶斯定理
聚焦
bio-photonics
scattering
transmission matrix
Bayesian theorem
focusing