基于全球视角下的中国结核病负担现状与趋势分析

Analysis on the status and trend of TB burden in China from the global views

目的分析中国1990-2017年结核病的患病、发病、死亡、伤残调整寿命年(disability adjusted life year,DALY)的现状及趋势,为结核病的防控提供参考依据。方法从健康指标和评估研究所(institute for health metrics and evaluation,IHME)网站获取1990-2017年中国、美国、印度、日本和全球的结核病(标化)患病率、(标化)发病率、(标化)死亡率、(标化)DALY率等指标,对比分析这些指标随年份变化情况。结果2017年中国结核病的患病率、发病率、死亡率、DALY率的高年龄组高于低年龄组。结核病患病率、发病率、死亡率、DALY率均是男性大于女性,患病率男性、女性分别为29641.59/10万、28803.26/10万,发病率男性、女性分别为72.23/10万、44.85/10万,死亡率男、女分别为3.85/10万、1.67/10万,DALY率男性、女性分别为156.95/10万、84.73/10万。在1990-2017年间,结核病的患病率从1990年的32178.39/10万下降至2017年的29231.30/10万,结核病的发病率从1990年的141.83/10万下降到2017年的58.83/10万,结核病的死亡率从1990年的13.82/10万下降到2017年的2.78/10万,结核病的DALY率从1990年的582.87/10万下降到2017年的121.60/10万。结论1990-2017年间中国结核病的疾病负担下降明显,但与发达国家比较仍有一定差距,仍需做出进一步努力,降低结核病的发病率与死亡率。

Objective To analyze the status and trends for the prevalence,morbidity,mortality,and DALY of tuberculosis(TB)in China from 1990 to 2017,so as to provide scientific basis for TB prevention and control.Methods From 1990 to 2017 in China,the United States,India,Japan,and the global,the TB(standardized)prevalence,(standardized)morbidity,(standardized)mortality,and(standardized)DALY rates were obtained from Institute for Health Metrics and Evaluation(IHME)website,and comparative analysis of changes in these indicators with years were carried out.Results In 2017,the prevalence,morbidity,mortality,and DALY rate of TB in China were higher in the high-age group than in the low-age group.The prevalence,morbidity,mortality,and DALY rates were all higher for males than females.The prevalence was 29641.59/100000 and 28803.26/100000 for male and female,respectively.The male and female mortality rates were 72.23/100000 and 44.85/100000.The male and female mortality rates were 3.85/100000 and 1.67/100000,and the DALY rate of male and female were 156.95/100000 and 84.73/100000.From 1990 to 2017,the prevalence of TB decreased from 32178.39/100000 in 1990 to 29231.80/100000 in 2017,the morbidity rate of TB decreased from 141.83/100000 in 1990 to 58.83/100000 in 2017,the mortality rate of TB decreased from 13.82/100000 in1990 to 2.78/100000 in 2017,and the DALY rate of TB decreased from 582.87/100000 in 1990 to 121.60/100000 in 2017.Conclusions The burden of TB in China declined markedly from 1990 to 2017.Although some progress has been made in the prevention and treatment of TB in China,but there is still a certain gap compared with developed countries.It is still necessary to further reduce the morbidity rate and mortality rate of TB.