小剂量阿司匹林结合低分子肝素钠治疗复发性流产的预后分析

Prognosis analysis of low dose aspirin combined with low molecular weight heparin sodium in the treatment of recurrent abortion

目的:分析小剂量阿司匹林结合低分子肝素钠治疗复发性流产的预后效果。方法:2017年12月-2018年12月收治复发性流产患者62例,随机分为两组,各31例。参照组给予常规保胎治疗;试验组在常规保胎基础上联合低分子肝素钠治疗,在孕4~5个月改口服阿司匹林。比较两组凝血功能指标水平及妊娠结局。结果:试验组凝血功能指标水平及妊娠结局均优于参照组,差异有统计学意义(P<0.05)。结论:小剂量阿司匹林结合低分子肝素钠治疗复发性流产,可以提高治疗效果,降低流产风险,进而改变妊娠结局。

Objective:To explore the prognosis effect of low dose aspirin combined with low molecular weight heparin sodium in the treatment of recurrent abortion.Methods:From December 2017 to December 2018,62 patients with recurrent abortion were selected and randomly divided into two groups with 31 cases in each group.The control group was given conventional prevent miscarriage treatment;the experimental group was treated with low molecular weight heparin sodium on the basis of conventional prevent miscarriage treatment,at 4 to 5 months of gestation,aspirin was taken orally.We compared the levels of coagulation indexes and pregnancy outcomes between the two groups.Results:In the experimental group,coagulation index and pregnancy outcome were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The application of low dose aspirin combined with low molecular weight heparin sodium in the treatment of recurrent abortion can improve the effect of treatment,reduce the risk of abortion,and then change the outcome of pregnancy.