阿奇霉素辅助治疗老年慢性阻塞性肺疾病的效果及对肺功能的影响分析

The effect of azithromycin adjuvant therapy on chronic obstructive pulmonary disease in the elderly and its influence on pulmonary function

目的:分析阿奇霉素辅助治疗老年慢性阻塞性肺疾病的效果及对肺功能的影响。方法:2018年1月-2019年1月收治老年慢性阻塞性肺疾病患者80例,按不同治疗方案分为两组,各40例。对照组采取常规治疗方法;观察组采取阿奇霉素辅助治疗。比较两组临床疗效及炎性因子水平。结果:观察组治疗总有效率高于对照组,治疗6个月后肺功能及炎性因子各项指标水平均显著优于对照组,差异有统计学意义(P<0.05)。结论:阿奇霉素辅助治疗老年慢阻性肺疾病具有良好临床效果,可明显改善老年患者肺功能,减少气道炎性反应。

Objective:To explore the effect of azithromycin adjuvant therapy on chronic obstructive pulmonary disease in the elderly and its influence on pulmonary function.Methods:From January 2018 to January 2019,80 elderly patients with chronic obstructive pulmonary disease were selected.According to different treatment schemes,they were divided into two groups with 40 cases in each group.The control group was treated with conventional therapy;the observation group was treated with azithromycin adjuvant therapy.We compared the clinical efficacy and the level of inflammatory factors between the two groups.Results:In the observation group,the total effective rate was higher than that in the control group,after 6 months of treatment,the indexes of pulmonary function and inflammatory factors were significantly better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The effect of azithromycin adjuvant therapy on chronic obstructive pulmonary disease in the elderly is good,it can obviously improve the lung function of the elderly patients and reduce the airway inflammation.