亚低温联合依达拉奉在脑出血患者中的应用

Application of Mild Hypothermia Combined with Edaravone in Patients with Cerebral Hemorrhage

目的积极探讨亚低温联合依达拉奉对脑出血患者日常生活活动能力及生活质量的影响。方法根据随机双盲法将淮滨县中医院2017年6月-2018年12月期间收治的脑出血患者92例进行分组。92例患者均予以口服阿司匹林肠溶片、指导锻炼等常规治疗,对照组(46例)实施依达拉奉治疗,观察组(46例)在对照组基础上加以接受亚低温干预模式。对两组患者的日常生活活动能力及生活质量进行调查分析。结果治疗前两组患者的Barthel评分及生活质量量表评分相比,差异无统计学意义(P>0.05);观察组患者在接受联合治疗后的Barthel评分明显高于治疗前及对照组患者,差异有统计学意义(P<0.05);观察组患者在联合治疗后的生活质量问卷评分明显高于对照组患者,差异有统计学意义(P<0.05)。结论对脑出血患者实行亚低温联合依达拉奉模式,可以明显改善脑出血患者的日常生活活动能力及生活质量,值得推广应用。

Objective To explore the effect of mild hypothermia combined with edaravone on activities of daily living and quality of life in patients with cerebral hemorrhage. Methods 92 patients with cerebral hemorrhage admitted to the hospital from June,2017 to December, 2018 were divided into two groups according to random double-blind method. 92 patients were given routine treatment, including oral aspirin enteric-coated tablets and exercise guidance. The control group(46 cases)received edaravone treatment, while the observation group(46 cases)received mild hypothermia intervention mode on the basis of the control group.The activities of daily living and quality of life of the two groups were investigated and analyzed. Results There was no significant difference in Barthel score and QOL score between the two groups before treatment(P>0.05). The Barthel score of the observation group after combined treatment was significantly higher than that of the control group before treatment(P<0.05). The QOL score of the observation group was significantly higher than that of the control group after combined treatment. The difference was significant(P<0.05). Conclusion Mild hypothermia combined with edaravone can significantly improve the activity of daily living and quality of life in patients with cerebral hemorrhage, which is worthy of promotion.