探究1型糖尿病患者伴发抑郁症的危险因素

Exploration of the Risk Factors of Type 1 Diabetes with Depression

目的探讨1型糖尿病患者合并抑郁症的危险因素,并探讨相应的干预策略。方法回顾性分析在惠州市第三人民医院就诊的66例1型糖尿病患者的临床资料,根据患者是否合并抑郁症分成实验组(30例)与对照组(36例),采取单因素分析及多因素logistic回归分析1型糖尿病患者合并抑郁症的危险因素。结果单因素分析结果,在年龄、性别上实验组与对照组相比差异无统计学意义(P>0.05),而在其他指标上两组差异有统计学意义(P<0.05);将单因素分析结果中显示有差异的指标作为变量,行多因素分析患者糖化血红蛋白、体重指数、合并视网膜病变(DR)、糖尿病肾病(DN)及糖尿病神经病变(DNP)为引起1型糖尿病伴发抑郁症的危险因素。结论 1型糖尿病患者由多种因素可引起抑郁症,为此临床中需加强干预,以改善患者的预后。

Objective To investigate the risk factors of type 1 diabetes mellitus complicated with depression,and to explore the corresponding intervention strategies. Methods The clinical data of 66 patients with type 1 diabetes were retrospectively analyzed, and the patients were divided into experimental group(30 cases) and control group(36 cases) according to whether the patients were complicated with depression. Univariate analysis and multivariate logistic regression were used to analyze the risk factors of type 1 diabetes patients with depression. Results Univariate analysis showed that there was no significant difference between the experimental group and the control group in age and gender(P>0.05),while there was significant difference between the two groups in other indicators(P<0.05). Univariate analysis was performed using variables that showed differences in univariate analysis results,and multivariate analysis was performed on glycosylated hemoglobin body mass index,combined with DR,DN and DNP as risk factors for type 1 diabetes with depression. Conclusion For patients with type 1 diabetes,multiple factors can cause depression,so it is necessary to strengthen clinical intervention to improve the prognosis of patients.