中西医结合治疗手足口病临床观察

Clinical Observation on Integrated Traditional Chinese and Western Medicine in the Treatment of Hand-Foot-Mouth Disease

目的分析手足口病应用利巴韦林气雾剂与蓝芩口服液联合治疗的效果及安全性。方法选取2017年1月-2018年12月收治的手足口病患者90例,根据治疗方法不同分为研究组与对照组(n=45),对照组给予利巴韦林气雾剂治疗,研究组联合应用利巴韦林气雾剂与蓝芩口服液治疗,对比2组临床疗效及不良反应发生情况。结果研究组退热时间为(1.1±0.3)d,疱疹结痂与消退时间分别为(2.2±0.5)d和(3.8±1.1)d,开始进食时间为(2.1±0.4)d,均好于对照组,差异有统计学意义(P<0.05)。研究组临床有效率93.3%显著好于对照组73.3%,差异有统计学意义(P<0.05)。研究组不良反应发生率为8.9%,对照组发生率为13.3%,差异无统计学意义(P>0.05)。结论手足口病应用利巴韦林气雾剂结合蓝芩口服液治疗的临床效果显著,且不良反应少,可推广应用。

Objective To analyze the efficacy and safety of ribavirin aerosol and Lanqin oral liquid in the treatment of hand-foot-mouth disease.Methods Ninety patients with hand-foot-mouth disease admitted to our hospital from January 2017 to December 2018 were enrolled.The study group was divided into study group and control group according to different treatment methods,with 45 cases in each group.The control group was given ribavirin aerosol.The study group was treated with ribavirin aerosol and Lanqin oral solution.The clinical efficacy and adverse reactions of the two groups was compared.Results In the study group,the time of fever was(1.1±0.3)days,and the time of herpes zoster and regression was(2.2±0.5)days and(3.8±1.1)days,respectively,the starting time was(2.1±0.4)days.Comparing with the control group,the difference was statistically significant(P<0.05).The clinical effective rate of the study group was 93.3%,which was significantly better than that of the control group(73.3%).The difference was statistically significant(P<0.05).The incidence of adverse reactions in the study group was 8.9%,and the incidence in the control group was 13.3%.The difference was not statistically significant(P>0.05).Conclusion The clinical effect of ribavirin aerosol combined with Lanqin oral liquid in hand-foot-mouth disease is significant,and there are few adverse reactions,which can be promoted and applied.