茵陈蒿汤联合恩替卡韦治疗重症化趋势乙型病毒性肝炎临床观察

Clinical Observation on Yinchenhao Decoction Combined with Entecavir in the Treatment of Severe Trend Viral Hepatitis B

目的探究加味茵陈蒿汤联合恩替卡韦治疗重症化趋势乙型病毒性肝炎的临床研究。方法将52例乙型病毒性肝炎患者作为研究对象,随机分成A组与B组,每组26例。A组应用恩替卡韦治疗方式,B组采用加味茵陈嵩汤联合恩替卡韦治疗方式。观察2组治疗后肝功能情况与临床相关指标情况。结果治疗后,B组丙氨酸转移酶(ALT)、天冬氨酸转移酶(AST)、白蛋白(ALB)、总胆红素(TBIL)指标均优于A组(P<0.05);B组治疗后纤维蛋白原、凝血酶时间、活化部分凝血酶时间、凝血酶原时间明显好于A组(P<0.05)。结论加味茵陈蒿汤联合恩替卡韦治疗重症化趋势乙型病毒性肝炎的临床效果较为显著,值得广泛推广。

Objective To explore the clinical effect of Yinchenhao decoction combined with entecavir in the treatment of severe trend hepatitis B.Methods 52 patients with hepatitis B in our hospital were randomly divided into group A and group B.Group A was treated with entecavir,while group B was treated with modified Yinchensong decoction combined with entecavir.The liver function and clinical related indexes were observed in the two groups after treatment.Results After treatment,the indexes of alanine aminotransferase(ALT),aspartate aminotransferase(AST),albumin(ALB),total bilirubin(TBIL)in group B were better than those in group A(P<0.05),and the indexes of fibrinogen,thrombin time,activated partial thrombin time and prothrombin time in group B were better than those in group A(P<0.05).Conclusion Yinchenhao decoction combined with entecavir has a significant clinical effect in the treatment of severe trend hepatitis B,which is worthy of wide promotion.